Dutasteride is indicated for the treatment of symptomatic benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. It can also be used in combination with tamsulosin for the treatment of BPH in men who have an enlarged prostate gland.

Benign prostatic hyperplasia (BPH)

The recommended dosage of Dutasteride is 0.5 mg once daily, with or without food. The capsule should be swallowed whole, without crushing or chewing.

The most common adverse reactions of Dutasteride are-

• Impotence and decreased libido
• Ejaculation disorders
• Breast disorders, including breast enlargement and tenderness
• Allergic reactions, such as rash, itching, and hives
• Testicular pain
• Depression

Low libido

Breast Tenderness

Infertility

Gynecomastia

• Dutasteride reduces serum prostate-specific antigen (PSA) concentration by approximately 50%. However, any confirmed increase in PSA while on Dutasteride may signal the presence of prostate cancer and should be evaluated, even if those values are still within the normal range for untreated men. 
• Dutasteride may increase the risk of high-grade prostate cancer.
• Assess patients to rule out other urological diseases, including prostate cancer, prior to prescribing Dutasteride.
• Women who are pregnant or could become pregnant should not handle Dutasteride Capsules due to potential risk to a male fetus. 
• Patients should not donate blood until 6 months after their last dose of Dutasteride.