Name Doxycycline Hydrochloride + Tylosin Tartrate
Classes Antiinfective Agent
Antibiotic
Antibiotic Combination
Diseases Gastrointestinal Infection
RTI (Respiratory Tract Infection)
Veterinary Infection

Doxycycline Hydrochloride + Tylosin Tartrate

Doxycycline Hydrochloride + Tylosin Tartrate is a combination of two antibiotics that are commonly used in veterinary medicine. Doxycycline is a tetracycline antibiotic that works by inhibiting bacterial protein synthesis. Tylosin is a macrolide antibiotic that works by inhibiting bacterial protein synthesis.

 

Doxycycline Hydrochloride + Tylosin Tartrate is indicated in  gastrointestinal and respiratory infections caused by tylosin and doxycycline sensitive micro-organisms, like Bordetella, Campylobacter, Chlamydia, E. coli, Haemophilus, Mycoplasma, Pasteurella, Rickettsia, Salmonella, Staphylococcus, Streptococcus and Treponema spp. in calves, goats, poultry, sheep and swine.

 

  • For oral administration only.
  • Calves, goats and sheep: Twice daily, 5 g per 100 kg body weight for 3 - 5 days.
  • Poultry and swine: 1 kg per 1000 - 2000 litres of drinking water for 3 - 5 days. 
  • For pre-ruminant calves, lambs and kids only.

The following side effects may appear in the treated animals-

  • Discoloration of teeth in young animals
  • Hypersensitivity reactions
  • Diarrhea
  • The antibiotic combination must be withdrawn before slaughter in the following timely manner-
    • Calves, goats and sheep : 14 days.
    • Swine : 8 days.
    • Poultry : 7 days.
  • Not for use in animals from which milk or eggs are produced for human consumption.

Contraindication

  • Contraindicated in animals with Hypersensitivity to tetracyclines and/or tylosin.
  • Concurrent administration of penicillins, cephalosporins, quinolones and cycloserine is contraindicated.
  • Administration to animals with a seriously impaired hepatic function.
  • Administration to animals with an active microbial digestion.