Name Procain Penicillin G
Classes Antiinfective Agent
Antibiotic
Penicillin
Diseases Anthrax
Bite
Cellulitis
Diphtheria
Infectious Disease
Pneumonia
Syphilis

Procain Penicillin G

Procaine penicillin G is a beta lactam antibiotic that kills bacteria by inhibiting cell wall synthesis. It is injected in a muscle.

Procaine penicillin is indicated for the following infections-

  • Gonorrhea caused by Penicillin sensitive micro-organisms
  • Endocarditis
  • Gas-gangrene following amputation
  • Pneumonia
  • Bejel 
  • Pinta 
  • Yaws

Procaine penicillin G is available as intramuscular injections only.

Adults: 4,00,000 units once daily or twice daily.
Children: Over 25 kg as for adults; under 25 kg reduce proportionally. In severe cases dose may be doubled.

Side effects associated with procaine benzyl penicillin include-

  • Injection site pain

Procaine related-

  • Asthenia
  • Anxiety

Penicillin related-

  • Nausea
  • Headache
  • Rash
  • Diarrhea
  • Caution should be exercised during injection to avoid nerve damage.
  • Some patients may show hypersensitivity reactions to penicillin. In such cases treatment should be stopped immediately.
  • Superinfection of resistant organisms like C.difficile may occur.
  • Dosage should be adjusted for renally impaired patients.

Contraindication

Contraindicated in patients hypersensitive to penicillin or other beta lactam antibiotics, such as-

There is no known contraindications of the drug in terms of food and drinks.

There is no known contraindications of the drug in terms of health conditions.