Name Dorzolamide + Timolol
Classes Dermatological/Topical Agent
Ophthalmic Preparation
Glaucoma Agent
Diseases Glaucoma
Ophthalmic Disease

Dorzolamide + Timolol

Dorzolamide + Timolol is a combinational eye drop solution that contains two medicines, dorzolamide hydrochloride called an ophthalmic carbonic anhydrase inhibitor and timolol maleate called a beta-blocker.

Dorzolamide + Timolol is indicated for the-

  • reduction of elevated intraocular pressure (IOP) in patients with open-angle glaucoma
  • ocular hypertension who are insufficiently responsive to beta-blockers
  • The dose is one drop of Dorzolamide + Timolol in the affected eye(s) two times daily.
  • If more than one topical ophthalmic drug is being used, the drugs should be administered at least five minutes apart

How to administer eye drops:

Commonly associated side effects include-

  • eye burning
  • eye stinging
  • eye redness
  • blurred vision
  • eye tearing
  • eye itching
  • a bitter, sour, or unusual taste after putting in your eyedrops
  • Only for ophthalmic use.
  • Patients should remove their contact lenses before using this preparation and wait 15 minutes before putting them back in.
  • Dorzolamide + Timolol contains dorzolamide, a sulfonamide that is absorbed systemically despite being applied topically. As a result, unpleasant responses similar to those seen with sulfonamides may develop when Dorzolamide + Timolol is applied topically.

Contraindication

Dorzolamide + Timolol contraindicated in patients hypersensitive to any component of the product and other sulfonamides-

 

Dorzolamide + Timolol is contraindicated in the following health conditions-

  • reactive airway disease
  • sinus bradycardia, sick sinus syndrome, sino-atrial block, second or third degree atrioventricular block not controlled with pacemaker, overt cardiac failure, cardiogenic shock
  • severe kidney problems