Bisoprolol hemifumarate is indicated for the following conditions-

• Hypertension (Hight Blood Pressure)
• Angina
• Heart Failure

Hypertension (Hight Blood Pressure)

Angina

Heart Failure

• Adults: Individual dosage adjustments should be made. It is suggested that you begin with 5 mg each day. The normal dose is 10 mg once daily, with a maximum dose of 20 mg per day being recommended.
• Patients with kidney disease: The dose should not exceed 10 mg once daily in patients with severe renal impairment (creatinine clearance 20 ml/min). This dosage may be divided in half in the future.

Commonly associated side effects of bisoprolol include-

• Bradycardia
• Cold extremities
• Gastrointestinal disturbances (nausea, diarrhea)
• Fatigue/ asthenia
• Dizziness

Bradycardia

Nausea

Diarrhea

Asthenia

• Bisoprolol should not be withdrawn abruptly. 
• Due to unopposed alpha-receptor mediated coronary artery vasoconstriction, it may increase the number and duration of angina attacks in patients with Prinzmetal's angina.
• If given to individuals with first-degree heart block, caution should be maintained due to its unfavorable effect on conduction time.
• May obscure hypoglycemic symptoms, particularly tachycardia.
• It's possible that it'll disguise the symptoms of thyrotoxicosis.
• As a result of its pharmacological activity, it will lower heart rate. When a patient is being treated for a condition that could be caused by a sluggish heart rate and their pulse rate drops to less than 50–55 beats per minute at rest, the dose should be lowered.