Medicine details

ImageDapsone 100
NameDapsone 100
DosageTablet
Generic NameDapsone
Classes Dermatological/Topical Agent
Topical Antiinfective Agent
Antiacne Agent
Diseases Leprosy
Lesions
Skin Disorder
CompanyEDCL (Dhaka)

Drug Package Details

Strength100 mg
Storage Condition
Origin CountryBangladesh
Commercial Pack1000
Price per pack210.00
Cost per pack184.80
Package unit25 tabs strip
Price per unit0.21
Cost per unit0.18
Discount0
Coupon
Remarks

Dapsone

Dapsone belongs to the class of antimicrobial agents, specifically a sulfone. Its mechanism of action involves inhibition of dihydropteroate synthase, an enzyme involved in the synthesis of folic acid in microorganisms. This leads to disruption of bacterial and parasitic DNA synthesis, making it effective against certain bacteria and protozoa.

Dapsone Gel is indicated for the topical treatment of acne vulgaris.

  • Apply twice daily.
  • Apply approximately a pea-sized amount of Dapsone Gel, 5%, in a thin layer to the acne affected area.
  • If there is no improvement after 12 weeks, treatment with Dapsone Gel, 5%, should be reassessed.
  • For topical use only. Not for oral, ophthalmic, or intravaginal use.

Most common adverse reactions (incidence ≥ 10%) are oiliness/peeling, dryness and erythema at the application site.

  • Methemoglobinemia: Cases of methemoglobinemia have been reported. Discontinue Dapsone gel if signs of methemoglobinemia occur 
  • Hematologic Effects: Some subjects with G6PD deficiency using Dapsone Gel developed laboratory changes suggestive of hemolysis

Contraindication