| Name | Drotaverine Hydrochloride |
| Classes |
Gastrointestinal Agent Antispasmodic |
| Diseases |
Labor Neuromascular Disorder Renal Colic Spasm |
Bangla
EnglishDrotaverine Hydrochloride
Drotaverine hydrochloride is a smooth muscle relaxant. Drotaverine hydrochloride inhibits phosphodiesterase enzyme, leading to an increase in cyclic adenosine monophosphate (cAMP) levels. This results in smooth muscle relaxation, particularly in the gastrointestinal tract and blood vessels.
Drotaverine hydrochloride is indicated for the treatment of smooth muscle spasms associated with various conditions, including irritable bowel syndrome, biliary colic, renal colic, and dysmenorrhea.
- The dosage may vary based on the specific indication and individual patient response.
- Standard Dosage: 40 to 80 mg three times a day, administered orally.
- Dosage adjustments may be made based on the severity of symptoms.
Common adverse reactions associated with drotaverine include-
- Nausea
- Headache
- Dizziness
- Gastrointestinal discomfort
- Palpitations
- Caution is advised in patients with a history of hypotension.
- Use with caution in patients with known hypersensitivity to drotaverine hydrochloride.
- Monitoring is recommended for patients with severe hepatic or renal impairment.
Contraindication
Known hypersensitivity to drotaverine hydrochloride.
None known.
None known.