Name Docosanol
Classes Antiinfective Agent
Dermatological/Topical Agent
Topical Antiinfective Agent
Diseases Cold Sore
Fever Blister
Itching
Pain
Skin Disorder
Tingling

Docosanol

Docosanol is a topical antiviral medication. Docosanol inhibits the fusion of the herpes simplex virus (HSV) with the host cell membrane. By preventing this fusion, the drug interferes with the entry of the virus into host cells, reducing viral replication and spread.

Docosanol is indicated for treating recurrent herpes labialis (cold sores) caused by the herpes simplex virus.

  • Apply a sufficient amount of docosanol cream to cover the cold sore and the surrounding area.
  • The recommended frequency of application is every 2 hours during waking hours for a period of 4 days.
  • Apply the cream topically to the affected area, following proper hygiene and handwashing.

Adverse reactions of Docosanol are listed below-

  • Headache
  • Skin irritation at the application site
  • Rash
  • Itching or burning sensation
  • Dry or flaky skin

Allergic Reactions:

  • Monitor for signs of allergic reactions, and discontinue use if they occur.
  • Seek medical attention for severe allergic reactions, such as swelling or difficulty breathing.

Avoid Ophthalmic Use:

  • Docosanol is for external use only and should not be used in or near the eyes.
  • In case of accidental eye exposure, rinse thoroughly with water.

Use in Pregnancy and Lactation:

  • The safety of docosanol during pregnancy and lactation is not well-established; use should be cautious, and the potential benefits should outweigh the risks.

Avoid Sexual Activity:

  • Docosanol is not intended for use as a preventive measure, and sexual activity should be avoided when the cream is applied.

Contraindication

Docosanol is contraindicated in individuals with known hypersensitivity to docosanol or any of the components in the formulation.