Alfuzosin Hydrochloride is indicated for the treatment of symptoms of benign prostatic hyperplasia (BPH) such as difficulty in starting urination, weak urine flow, and frequent urination.

Benign prostatic hyperplasia (BPH)

• The usual recommended dose for adults is one 10 mg tablet once daily, preferably taken after the same meal each day.
• The tablet should be swallowed whole with water and should not be crushed or chewed.
• Patients with moderate to severe renal impairment should be started on a lower dose of 2.5 mg once daily.

The most common adverse reactions associated with alfuzosin hydrochloride include-

• dizziness
• headache
• fatigue
• orthostatic hypotension

Dizziness

Headache

Fatigue

Orthostatic Hypotension

• Alfuzosin Hydrochloride may cause dizziness, especially during the first few days of treatment or when the dose is increased. Patients should be advised to avoid activities requiring alertness such as driving or operating machinery until they know how the medication affects them.
• Patients should be advised to avoid consuming grapefruit or grapefruit juice while taking Alfuzosin Hydrochloride as it may increase the level of the drug in the blood, leading to increased side effects.
• Alfuzosin Hydrochloride should be used with caution in patients with hepatic impairment as it may increase the risk of adverse reactions.
• Patients with a history of low blood pressure or taking medications that lower blood pressure should be monitored closely while taking Alfuzosin Hydrochloride.
• Alfuzosin Hydrochloride should be used with caution in patients with a history of prolonged QT interval, arrhythmias, or those taking medications that prolong QT interval as it may increase the risk of torsades de pointes.