| Name | Dextran 40 + Dextrose |
| Classes |
Nutritional Supplement Nutritient Solution |
| Diseases |
Blood Disorder Dehydration Fluid Depletion Hypovolemic Shock Pulmonary Embolism |
Bangla
EnglishDextran 40 + Dextrose
Dextran is a complex branched glucan (polysaccharide derived from the condensation of glucose). Dextran causes expansion of plasma volume. It is administered intravenously when there is sudden loss of dangerous amount of blood.
Dextrose is a monosaccharide which is a source of calorie and water for hydration.
Dextran 40 + Dextrose is indicated for the following conditions-
- Hypovolemic shock
- Weakness
- Source of calorie when needed
- Thrombosis
- Pulmonary embolism
Hypovolemic shock
- As dextran (IV) 40 (10 percent solution): 10 mL/kg/day for up to 5 days.
Thromboembolic disorders:
- 500 ml on the first day, 500 ml on the second day, and so on for the next ten days. Prophylaxis for thromboembolic diseases after surgery. 500 mL before, during, and after operation. May repeat dose next day and continue treatment on alternate days for up to 10 days in high-risk patients.
- Up to 5 ml/kg in neonates and 10 ml/kg in children.
Following side effects may appear-
- Congestive heart failure
- Mild hypotension
- Tightness of chest
- Thrombocytopenia
- Anaphylaxis
- Injection site infection/phlebitis
- Acute renal failure
- Acidosis (if NaCI soln used)
- Pulmonary edema
- Wheezing
Caution should be exercised in-
- Patients with or at risk of heart failure; active haemorrhage, diabetes mellitus, chronic liver failure, risk of pulmonary oedema.
- Renal and hepatic impairment. Pregnancy and lactation.
Correct dehydration prior to administration.
Not intended as a replacement for whole blood or blood components.
Contraindication
Hypersensitivity to dextran or corn containing products.
None known.
None known.