Dexamethasone + Tobramycin is indicated for the following conditions-

• Eye infections
• Conjunctivitis
• Uveitis
• Eye inflammation (due to chemical/mechanical injury)

Eye Infection

Conjunctivitis

Eye inflammation

• Every four to six hours, place one drop into the conjunctival sac(s). During the first 24 to 48 hours, increase the dosage to one drop every two hours. As clinical signs improve, the frequency should be gradually reduced. It is critical not to discontinue therapy too soon.
• In the beginning, no more than 20 mL should be prescribed, and the prescription should not be refilled without further evaluation.

How to use the medication

Eye Drop

Eye Drops

Adverse reactions to corticosteroid/anti-infective combination drugs have occurred, which can be attributed to the corticosteroid component, the anti-infective component, or the combination. Exact incidence figures are unavailable due to a lack of a denominator of treated patients.

• Ocular hypertension
• Glaucoma
• Optic nerve damage
• Cataract
• Delayed wound healing
• Superinfection

Occular hypertension

Glaucoma

Cataract

Increase in IOP: Corticosteroid use for an extended period of time can cause glaucoma, which causes damage to the optic nerve and defects in visual acuity and field of vision. IOP should be monitored if this product is used for more than 10 days.

Sensitivity to aminoglycosides: Topically applied aminoglycosides may cause sensitization.

Cataract: Corticosteroid use may result in posterior subcapsular cataract formation.

Delayed healing: Steroid use after cataract surgery may cause healing to be delayed and increase the likelihood of bleb formation. Perforations have been reported with the use of topical steroids in diseases that cause thinning of the cornea or sclera. The initial prescription and renewal of the medication order should be made by a physician only after examination of the patient with the aid of magnification such as slit lamp bio-microscopy and, where appropriate, fluorescein staining.

Bacterial infections: Prolonged use of corticosteroids may suppress the host response and thus increase the hazard of secondary ocular infections. In acute purulent conditions, steroids may mask infection or enhance existing infection. If signs and symptoms fail to improve after 2 days, the patient should be re-evaluated.

Viral infections: Employment of a corticosteroid medication in the treatment of patients with a history of herpes simplex requires great caution. Use of ocular steroids may prolong the course and may exacerbate the severity of many viral infections of the eye (including herpes simplex).

Fungal infections: Fungal infections of the cornea are particularly prone to develop coincidentally with long-term local steroid application. Fungus invasion must be considered in any persistent corneal ulceration where a steroid has been used or is in use.