Name Dexamethasone + Neomycin + Polymixin
Classes Dermatological/Topical Agent
Topical Antiinfective Agent
Ophthalmic Preparation
Antiinfective and Steroid Combination
Diseases Inflammation
Ophthalmic Disease

Dexamethasone + Neomycin + Polymixin

Dexamethasone + Neomycin + Polymyxin is an anti-infective steroid combination in sterile suspension form for topical application. It is usually used to treat various inflammatory ophthalmic conditions.

Dexamethasone + Neomycin + Polymyxin indicated for the following conditions-

  • Eye infections
  • Conjunctivitis
  • Uveitis
  • Eye inflammation (due to chemical/mechanical injury)

Eye drops:

  • Adults and children 2 years of age and older: Use one or two drops in the affected eye 4 to 6 times a day. Your doctor may tell you to use the drops more often during severe infections.
  • Children younger than 2 years of age: Use and dose must be determined by your doctor.

Eye ointment

  • Adults: Apply a small amount (about 1/2 an inch) into the eye 3 or 4 times a day.
  • Children: Use and dose must be determined by your doctor.

How to use the medication

1. Eye Drop
2. Eye ointment

Adverse reactions to corticosteroid/anti-infective combination drugs have occurred, which can be attributed to the corticosteroid component, the anti-infective component, or the combination. Exact incidence figures are unavailable due to a lack of a denominator of treated patients.

  • Ocular hypertension
  • Glaucoma
  • Optic nerve damage
  • Cataract
  • Delayed wound healing
  • The initial prescription and renewal of the medication order beyond 20 mL of Dexamethasone + Neomycin + Polymyxin should be made by a physician only after a thorough examination of the patient using magnification, such as slit lamp bio-microscopy and, if necessary, fluorescein staining.
  • If the patient's signs and symptoms do not improve after two days, he or she should be reevaluated.
  • Because fungal infections of the cornea are more likely to develop concurrently with long-term corticosteroid use, fungal invasion should be suspected in any persistent corneal ulceration where a corticosteroid has been used or is being used.
  • When necessary, fungal cultures should be obtained.
  • IOP should be monitored if this product is used for more than 10 days.
  • Prolonged use of topical anti-bacterial agents may give rise to overgrowth of non-susceptible organisms including fungi.
  • If the inflammation or pain lasts more than 48 hours or worsens, the patient should be advised to stop taking the medication and consult a doctor.

Contraindication

Contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids, such as-

Contraindicated in most viral infections of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures.